Best Price CAS 51-05-8   99% Procaine hydrochloride

Best Price CAS 51-05-8 99% Procaine hydrochloride

DESCRIPTION

Procaine hydrochloride is a kind of local anesthetic drug, which can temporarily block the conduction of nerve fibers and has anesthetic effect, strong effect, low toxicity, and no addiction. But it has weak penetration of skin and mucosa, and is not suitable for surface anesthesia. The aqueous solution of the product was stable between pH3.0 and 5.0. Therefore, when procaine hydrochloride injection is prepared, it is generally necessary to add acid to adjust the pH between 3.3 and 5.5, and strictly control the sterilization temperature and time. It is appropriate to sterilize with steam at 100℃ for 30 minutes, and attention should be paid to cover the light and keep it closed. The arylprimary amino group in the structure of this product in dilute hydrochloric acid, and nitrite Chemicalbook sodium to form diazonium salt, and alkaline β-naphthyl phenol coupling reaction, the formation of scarlet azo compounds. Properties Procaine hydrochloride at room temperature is a white fine needle-like crystal or crystalline powder, odorless, slightly bitter and numb taste, soluble in water, soluble in ethanol, slightly soluble in chloroform, almost insoluble in ether. The ester bond in the structure of procaine hydrochloride can be hydrolyzed to produce p-aminobenzoic acid and diethylaminoethanol, and under certain conditions, p-aminobenzoic acid can be further decarboxylated to produce toxic aniline. The structure of procaine hydrochloride has aryl primary amino group, which is easy to oxidise color change. pH value, temperature, ultraviolet light, oxygen and metal ions can accelerate the oxidation color change.
  • Published

    2022-12-20 16:12:42

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